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1

Influence of Region-Specific Alterations of Neuropeptidase Content on the Catabolic Fates of Neuropeptides in Alzheimer's Disease

Carole Ichai, Nathalie Chevallier, Pia Delaere, Pascal Dournaud, Jacques Epelbaum, Jean-Jacques Hauw, Jean-Pierre Vincent, Frédéric Checler

Journal:

Journal of Neurochemistry

Year:

1994

Language:

english

File:

PDF, 1.21 MB

english, 1994

2

Neuropeptidases in cortical areas and in the cerebellum in Alzheimer's disease: Region-specific alterations lead to modified catabolic fate of somatostatin(1–14)

C. Ichai, N. Chevallier, P. Delaere, P. Dournaud, J. Epelbaum, J.J. Hauw, J.P. Vincent, F. Checler

Journal:

Year:

1993

Language:

english

File:

PDF, 143 KB

english, 1993

3

P4-317 Gamma-secretase inhibitors: a critical evaluation of their potential therapeutic use in Alzheimer disease

Checler, Frédéric

Journal:

Neurobiology of Aging

Year:

2004

Language:

english

File:

PDF, 158 KB

english, 2004

4

Nuclear p53-mediated repression of autophagy involves PINK1 transcriptional down-regulation

Goiran, Thomas, Duplan, Eric, Rouland, Lila, el Manaa, Wejdane, Lauritzen, Inger, Dunys, Julie, You, Han, Checler, Frédéric, Alves da Costa, Cristine

Journal:

Cell Death & Differentiation

Year:

2018

Language:

english

File:

PDF, 1.66 MB

english, 2018

5

Chronic fornix deep brain stimulation in a transgenic Alzheimer’s rat model reduces amyloid burden, inflammation, and neuronal loss

Leplus, Aurelie, Lauritzen, Inger, Melon, Christophe, Kerkerian-Le Goff, Lydia, Fontaine, Denys, Checler, Frederic

Journal:

Brain Structure and Function (Anatomy and Embryology 1891-2006)

Year:

2018

Language:

english

File:

PDF, 17.83 MB

english, 2018

6

Days to criterion as an indicator of toxicity associated with human Alzheimer amyloid-β oligomers

Sam Gandy, Adam J. Simon, John W. Steele, Alex L. Lublin, James J. Lah, Lary C. Walker, Allan I. Levey, Grant A. Krafft, Efrat Levy, Frédéric Checler, Charles Glabe, Warren B. Bilker, Ted Abel, James

Journal:

Annals of Neurology

Year:

2010

Language:

english

File:

PDF, 1.19 MB

english, 2010

7

Neuropathology of preclinical and clinical lateonset Alzheimer's disease

Dr Juan C. Troncoso, Anne M. Cataldo, Rallph A. Nixon, Jody L. Barnett, Michael K. Lee, Frederic Checler, David R. Fowler, John E. Smialek, Barbara Crain, Lee J. Martin, Claudia H. Kawas

Journal:

Annals of Neurology

Year:

1998

Language:

english

File:

PDF, 486 KB

english, 1998

8

JLK isocoumarin inhibitors: Selective γ-secretase inhibitors that do not interfere with notch pathway in vitro or in vivo

A. Petit, A. Pasini, C. Alves da Costa, E. Ayral, J.F. Hernandez, C. Dumanchin-Njock, C.J. Phiel, P. Marambaud, S. Wilk, M. Farzan, P. Fulcrand, J. Martinez, D. Andrau, F. Checler

Journal:

Journal of Neuroscience Research

Year:

2003

Language:

english

File:

PDF, 304 KB

english, 2003

9

Synthesis of new 3-alkoxy-7-amino-4-chloro-isocoumarin derivatives as new β-amyloid peptide production inhibitors and their activities on various classes of protease

Frédéric Bihel, Gilles Quéléver, Hugues Lelouard, Agnès Petit, Cristine Alvès da Costa, Olivier Pourquié, Frédéric Checler, Annie Thellend, Philippe Pierre, Jean-Louis Kraus

Journal:

Bioorganic & Medicinal Chemistry

Year:

2003

Language:

english

File:

PDF, 548 KB

english, 2003

10

The C-terminal fragment of the Alzheimer's disease amyloid protein precursor is degraded by a proteasome-dependent mechanism distinct from γ-secretase

Janelle Nunan, Mark S. Shearman, Frédéric Checler, Roberto Cappai, Geneviève Evin, Konrad Beyreuther, Colin L. Masters, David H. Small

Journal:

Year:

2001

Language:

english

File:

PDF, 602 KB

english, 2001

11

Cholinesterases Display Genuine Arylacylamidase Activity but Are Totally Devoid of Intrinsic Peptidase Activities

Frédéric Checler, Jacques Grassi, Jean-Pierre Vincent

Journal:

Journal of Neurochemistry

Year:

1994

Language:

english

File:

PDF, 773 KB

english, 1994

12

Processing of the β-Amyloid Precursor Protein and Its Regulation in Alzheimer's Disease

Frédéric Checler

Journal:

Journal of Neurochemistry

Year:

1995

Language:

english

File:

PDF, 1.49 MB

english, 1995

13

Protein Kinase A Phosphorylation of the Proteasome: A Contribution to the α-Secretase Pathway in Human Cells

Philippe Marambaud, Sherwin Wilk, Frederic Checler

Journal:

Journal of Neurochemistry

Year:

1996

Language:

english

File:

PDF, 454 KB

english, 1996

14

Proteasome Contributes to the α-Secretase Pathway of Amyloid Precursor Protein in Human Cells

Philippe Marambaud, Nathalie Chevallier, Helene Barelli, Sherwin Wilk, Frederic Checler

Journal:

Journal of Neurochemistry

Year:

1997

Language:

english

File:

PDF, 636 KB

english, 1997

15

Stably Transfected Human Cells Overexpressing Rat Brain Endopeptidase 3.4.24.16: Biochemical Characterization of the Activity and Expression of Soluble and Membrane-Associated Counterparts

Bruno Vincent, Pascale Dauch, Jean Pierre Vincent, Frédéric Checler

Journal:

Journal of Neurochemistry

Year:

1997

Language:

english

File:

PDF, 1.04 MB

english, 1997

16

Constitutive and Protein Kinase C-Regulated Secretory Cleavage of Alzheimer's β-Amyloid Precursor Protein: Different Control of Early and Late Events by the Proteasome

Philippe Marambaud, Elvira Lopez-Perez, Sherwin Wilk, Frédéric Checler

Journal:

Journal of Neurochemistry

Year:

1997

Language:

english

File:

PDF, 958 KB

english, 1997

17

α-Secretase-Derived Product of β-Amyloid Precursor Protein Is Decreased by Presenilin 1 Mutations Linked to Familial Alzheimer's Disease

Karine Ancolio, Philippe Marambaud, Pascale Dauch, Frédéric Checler

Journal:

Journal of Neurochemistry

Year:

1997

Language:

english

File:

PDF, 751 KB

english, 1997

18

Mutant Presenilin 1 Increases the Levels of Alzheimer Amyloid β-Peptide Aβ42 in Late Compartments of the Constitutive Secretory Pathway

Suzana S. Petanceska, Mary Seeger, Frederic Checler, Sam Gandy

Journal:

Journal of Neurochemistry

Year:

2000

Language:

english

File:

PDF, 229 KB

english, 2000

19

Constitutive α-secretase cleavage of the β-amyloid precursor protein in the furin-deficient LoVo cell line: involvement of the pro-hormone convertase 7 and the disintegrin metalloprotease ADAM10

Elvira Lopez-Perez, Yue Zhang, Stuart J Frank, John Creemers, Nabil Seidah, Frédéric Checler

Journal:

Journal of Neurochemistry

Year:

2001

Language:

english

File:

PDF, 457 KB

english, 2001

20

The multiple paradoxes of presenilins : MINI REVIEW

Journal:

Journal of Neurochemistry

Year:

2001

Language:

english

File:

PDF, 228 KB

english, 2001

21

The caspase-derived C-terminal fragment of βAPP induces caspase-independent toxicity and triggers selective increase of Aβ42 in mammalian cells

Cécile Dumanchin-Njock, Cristine Alves Da Costa, Luc Mercken, Laurent Pradier, Frédéric Checler

Journal:

Journal of Neurochemistry

Year:

2001

Language:

english

File:

PDF, 552 KB

english, 2001

22

Overexpression of PrPc triggers caspase 3 activation: potentiation by proteasome inhibitors and blockade by anti-PrP antibodies

E. Paitel, C. Alves da Costa, D. Vilette, J. Grassi, F. Checler

Journal:

Journal of Neurochemistry

Year:

2002

Language:

english

File:

PDF, 301 KB

english, 2002

23

Thrombophlebitis of the Ovarian Vein With Free-Floating Thrombus in the Inferior Vena Cava

Reda Hassen-Khodja, Jean-Yves Gillet, Michel Batt, André Bongain, Michael Persch, Line Libo, Serge Declemy, Eric Checler, Pierre LeBas

Journal:

Annals of Vascular Surgery

Year:

1993

Language:

english

File:

PDF, 473 KB

english, 1993

24

Presenilins

Frédéric Checler

Journal:

Molecular Neurobiology

Year:

1999

Language:

english

File:

PDF, 975 KB

english, 1999

25

NACP/α-Synuclein, NAC, and β-amyloid pathology of familial Alzheimer's disease with the E184D presenilin-1 mutation: a clinicopathological study of two autopsy cases

Osamu Yokota, Seishi Terada, Hideki Ishizu, Hiroshi Ujike, Takeshi Ishihara, Hanae Nakashima, Minoru Yasuda, Yoshihiro Kitamura, Kenji Uéda, Frédéric Checler, Shigetoshi Kuroda

Journal:

Acta Neuropathologica

Year:

2002

Language:

english

File:

PDF, 796 KB

english, 2002

26

Variability and heterogeneity in Alzheimer's disease with cotton wool plaques: a clinicopathological study of four autopsy cases

Osamu Yokota, Seishi Terada, Hideki Ishizu, Hiroshi Ujike, Takeshi Ishihara, Masuyuki Namba, Yasuaki Hayashi, Tetsuya Nishinaka, Reiko Namba, Hanae Nakashima, Kenji Uéda, Frédéric Checler, Shigetoshi

Journal:

Acta Neuropathologica

Year:

2003

Language:

english

File:

PDF, 652 KB

english, 2003

27

Increased expression of neuronal cyclooxygenase-2 in the hippocampus in amyotrophic lateral sclerosis both with and without dementia

Osamu Yokota, Seishi Terada, Hideki Ishizu, Takeshi Ishihara, Hanae Nakashima, Aki Kugo, Kuniaki Tsuchiya, Kenji Ikeda, Toshiyuki Hayabara, Yuko Saito, Shigeo Murayama, Kenji Uéda, Frédéric Checler, S

Journal:

Acta Neuropathologica

Year:

2004

Language:

english

File:

PDF, 302 KB

english, 2004

28

Amyloid-β42 is preferentially accumulated in muscle fibers of patients with sporadic inclusion-body myositis

Gaetano Vattemi, Anna Nogalska, W. King Engel, Carla D’Agostino, Frederic Checler, Valerie Askanas

Journal:

Acta Neuropathologica

Year:

2009

Language:

english

File:

PDF, 374 KB

english, 2009

29

Light and Electron Microscopic Localization of the Neutral Metalloendopeptidase EC 3.4.24.16 in the Mesencephalon of the Rat

John Woulfe, Frederic Checler, Alain Beaudet

Journal:

European Journal of Neuroscience

Year:

1992

Language:

english

File:

PDF, 5.57 MB

english, 1992

30

Degradation of Neurotensin by Rat Brain Synaptic Membranes: Involvement of a Thermolysin-Like Metalloendopeptidase (Enkephalinase), Angiotensin-Converting Enzyme, and Other Unidentified Peptidases

Frederic Checler, Jean-Pierre Vincent, Patrick Kitabgi

Journal:

Journal of Neurochemistry

Year:

1983

Language:

english

File:

PDF, 973 KB

english, 1983

31

Inactivation of Neurotensin by Rat Brain Synaptic Membranes. Cleavage at the Pro10-Tyr11 Bond by Endopeptidase 24.11 (Enkephalinase) and a Peptidase Different from Proline-Endopeptidase

Frédéric Checler, P. C. Emson, J. P. Vincent, P. Kitabgi

Journal:

Journal of Neurochemistry

Year:

1984

Language:

english

File:

PDF, 752 KB

english, 1984

32

Inactivation of Neurotensin by Rat Brain Synaptic Membranes Partly Occurs Through Cleavage at the Arg8-Arg9 Peptide Bond by a Metalloendopeptidase

Frédéric Checler, J. P. Vincent, P. Kitabgi

Journal:

Journal of Neurochemistry

Year:

1985

Language:

english

File:

PDF, 419 KB

english, 1985

33

High-Affinity Receptor Sites and Rapid Proteolytic Inactivation of Neurotensin in Primary Cultured Neurons

Frédéric Checler, Jean Mazella, Patrick Kitabgi, Jean-Pierre Vincent

Journal:

Journal of Neurochemistry

Year:

1986

Language:

english

File:

PDF, 690 KB

english, 1986

34

Neurotensin-Metabolizing Peptidases in Rat Fundus Plasma Membranes

Frédéric Checler, Hélène Barelli, Chiu-Yin Kwan, Patrick Kitabgi, Jean-Pierre Vincent

Journal:

Journal of Neurochemistry

Year:

1987

Language:

english

File:

PDF, 578 KB

english, 1987

35

Peptidasic Activities Associated with Acetylcholinesterase Are Due to Contaminating Enzymes

Frédéric Checler, Jean-Pierre Vincent

Journal:

Journal of Neurochemistry

Year:

1989

Language:

english

File:

PDF, 479 KB

english, 1989

36

Monoclonal Antibodies Allow Precipitation of Esterasic but Not Peptidasic Activities Associated with Butyrylcholinesterase

F. Checler, J. Grassi, P. Masson, J. P. Vincent

Journal:

Journal of Neurochemistry

Year:

1990

Language:

english

File:

PDF, 562 KB

english, 1990

37

Neurotensin and Neuromedin N Are Differently Metabolized in Ventral Tegmental Area and Nucleus Accumbens

Frédéric Checler, Pascale Dauch, Yoshinori Masuo, Jean-Pierre Vincent

Journal:

Journal of Neurochemistry

Year:

1991

Language:

english

File:

PDF, 941 KB

english, 1991

38

Endopeptidase 24-16 in Murines: Tissue Distribution, Cerebral Regionalization, and Ontogeny

P. Dauch, Y. Masuo, J. P. Vincent, F. Checler

Journal:

Journal of Neurochemistry

Year:

1992

Language:

english

File:

PDF, 705 KB

english, 1992

39

Presenilin-directed inhibitors of γ-secretase trigger caspase 3 activation in presenilin-expressing and presenilin-deficient cells

Cristine Alves da Costa, Erwan Ayral, Jean-François Hernandez, Peter St George-Hyslop, Frédéric Checler

Journal:

Journal of Neurochemistry

Year:

2004

Language:

english

File:

PDF, 215 KB

english, 2004

40

Combined pharmacological, mutational and cell biology approaches indicate that p53-dependent caspase 3 activation triggered by cellular prion is dependent on its endocytosis

Claire Sunyach, Frédéric Checler

Journal:

Journal of Neurochemistry

Year:

2005

Language:

english

File:

PDF, 511 KB

english, 2005

41

APPε, the ε-secretase-derived N-terminal product of the β-amyloid precursor protein, behaves as a type I protein and undergoes α-, β-, and γ-secretase cleavages

Solveig Lefranc-Jullien, Claire Sunyach, Frédéric Checler

Journal:

Journal of Neurochemistry

Year:

2006

Language:

english

File:

PDF, 417 KB

english, 2006

42

Neprilysin activity and expression are controlled by nicastrin

R. Pardossi-Piquard, J. Dunys, G. Yu, P. St. George-Hyslop, C. Alves da Costa, F. Checler

Journal:

Journal of Neurochemistry

Year:

2006

Language:

english

File:

PDF, 392 KB

english, 2006

43

p53-Dependent control of cell death by nicastrin: lack of requirement for presenilin-dependent γ-secretase complex

Raphaëlle Pardossi-Piquard, Julie Dunys, Emilie Giaime, Marie-Victoire Guillot-Sestier, Peter St. George-Hyslop, Frédéric Checler, Cristine Alves da Costa

Journal:

Journal of Neurochemistry

Year:

2009

Language:

english

File:

PDF, 871 KB

english, 2009

44

Aminopeptidase A contributes to the N-terminal truncation of amyloid β-peptide

Jean Sevalle, Audrey Amoyel, Philippe Robert, Marie-Claude Fournié-Zaluski, Bernard Roques, Frédéric Checler

Journal:

Journal of Neurochemistry

Year:

2009

Language:

english

File:

PDF, 610 KB

english, 2009

45

Pharmacological evidences for DFK167-sensitive presenilin-independent γ-secretase-like activity

Jean Sevalle, Erwan Ayral, Jean-François Hernandez, Jean Martinez, Frédéric Checler

Journal:

Journal of Neurochemistry

Year:

2009

Language:

english

File:

PDF, 556 KB

english, 2009

46

The physiology of the β-amyloid precursor protein intracellular domain AICD

Raphaëlle Pardossi-Piquard, Frédéric Checler

Journal:

Journal of Neurochemistry

Year:

2012

Language:

english

File:

PDF, 203 KB

english, 2012

47

Journal of Neurochemistry special issue on Alzheimer’s disease: ‘amyloid cascade hypothesis – 20 years on’

Frédéric Checler, Anthony J. Turner

Journal:

Journal of Neurochemistry

Year:

2012

Language:

english

File:

PDF, 93 KB

english, 2012

48

10.1038/35074581

Petit, Agnès, Bihel, Frédéric, da Costa, Cristine Alvès, Pourquié, Olivier, Checler, Frédéric, Kraus, Jean-Louis

Journal:

Nature Cell Biology

Year:

2001

Language:

english

File:

PDF, 265 KB

english, 2001

49

10.1038/8438

Tabira, Takeshi, Chui, De-Hua, Tanahashi, Hiroshi, Ozawa, Kazuharu, Ikeda, Sachiya, Checler, Frédéric, Ueda, Otoya, Suzuki, Hiroshi, Araki, Wataru, Inoue, Haruhisa, Shirotani, Keiro, Takahashi, Keikic

Journal:

Nature Medicine

Year:

1999

Language:

english

File:

PDF, 994 KB

english, 1999

50

Amyloid-lowering isocoumarins are not direct inhibitors of γ-secretase

Petit, Agnes, Dumanchin-Njock, Cécile, Andrau, David, da Costa, Cristine Alves, Checler, Frédéric

Journal:

Nature Cell Biology

Year:

2002

Language:

english

File:

PDF, 465 KB

english, 2002

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